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Lusions: Early limited exposure to nitrosamines exacerbates the adverse effects of later chronic high dietary fat intake in promoting T2DM and neurodegeneration. The mechanism involves increased generation of ceramides and probably other toxic lipids in brain.Background The prevalence rates of Alzheimer's Disease (AD), Parkinson's disease (PD), obesity, type 2 diabetes mellitus (T2DM), and metabol
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Ughly the same level. Table 3 gives the results of the longitudinal analysis in which the same women were followed from one survey to another. There were some differences by the number of follow-ups (how early or late the woman was recruited) as well as by compliance with the surveys (did she skip some of the surveys, group "Intermittent surveys" in Table 3). In the groups with only three or twoTa
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Cpx (4 each), and clades A, F, CRF01_AE and CRF36_cpx (2 each). In addition, 22 of the studied viruses apparently had nef and gag genes from viruses belonging to different clades, with the majority (8/10) having either a nef or gag gene derived from CRF02_AG. Interestingly, five gag sequences (10 ) and three (5 ) nef sequences were neither obviously recombinant nor easily classifiable into any
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Anied with a higher tendency towards aggressive behaviour as a consequence to gasoline inhalation.11. 12.13. 14.AbbreviationsNa+, K+-ATPase: total adenosine triphosphatase; SOD: superoxide dismutase; AChE: acetylcholinesterase; GSH: reduced glutathione; TBARS: lipid peroxidation; DA: dopamine; NE: norepinephrine; 5-HT: serotonin; CNS: central nervous system; ROS: reactive oxygen species; MMT: meth
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On-alcoholic steatohepatitis (NASH), and AD [7-13]. The concept that chronic injury caused by exposure to alkylating agents could result in malignancy and/or tissue degeneration is not far-fetched given the facts that: 1) chronic exposures to tobacco nitrosamines cause both lung cancer and emphysema; and 2) treatment with streptozotocin (STZ), a nitrosamine-related compound, causes hepatocellular
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Ps were very similar by the studied background characteristics. Table 2 gives the prevalence of vasomotor symptoms according to a cross-sectional analysis. At the time of recruitment, about two thirds of the women reported vasomotor symptoms, and about a half regarded them as bothersome. In the survey a year later, less (53 ) of women reported vasomotor symptoms and a third found them bothersome.
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Ps were very similar by the studied background characteristics. Table 2 gives the prevalence of vasomotor symptoms according to a cross-sectional analysis. At the time of recruitment, about two thirds of the women reported vasomotor symptoms, and about a half regarded them as bothersome. In the survey a year later, less (53 ) of women reported vasomotor symptoms and a third found them bothersome.
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Cpx (4 each), and clades A, F, CRF01_AE and CRF36_cpx (2 each). In addition, 22 of the studied viruses apparently had nef and gag genes from viruses belonging to different clades, with the majority (8/10) having either a nef or gag gene derived from CRF02_AG. Interestingly, five gag sequences (10 ) and three (5 ) nef sequences were neither obviously recombinant nor easily classifiable into any
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