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Mor microenvironment and its role in promoting tumor growth. Oncogene. 2008;27(45):5904?2. 52. Zamarron BF, Chen W. Dual roles of immune cells and their factors in cancer development and progression. Int J Biol Sci. 2011;7(5):651?. 53. Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144(5):646?4. 54. Joven J, Guirro M, Marine-Casado R, Rodriguez-Gallego E, Menendez JA.
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Ither the leaded or unleaded group as compared with the control. On the contrary, dopamine was elevated in the cerebellum of leaded exposed group above both the unleaded gasoline and control. The fluctuations in the levels of dopamine in different brain areas may be related to the effects MMT which is an organic manganese (Mn) compound added to unleaded gasoline and the mechanisms of Mn neurotoxic
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Ecules or to relative reduction in acetylcholinesterase-containing neurons, thus potentiating cholinergic effects. In the present study, no statistical differences were detected among the serotonin levels of the cerebral cortex in the three groups; the control, the leaded and the unleaded. However, in the hypothalamus, hippocampus, cerebellum, the serotonin level was lower in the groups exposed to
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N male rats.Parameter Duration of aggression/sec GROUP Control Leaded gasoline Unleaded gasoline Tooth chattering 0.9 ?0.23 4.7 ?1.1 a** 4.4 ?0.92 a* Threat posture 1.5 ?0.54 6 ?1.2 a* 6.2 ?1.31 a* Leaping and biting 1.9 ?0.72 5.5 ?1.45 5.9 ?1.50 Boxing position 1 ?0.42 2.2 ?0.63 2.2 ?0.Values are expressed as means ?SE a: significantly different from the control group. Asterisks indicate the leve
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Is the study of Gutteridge and Halliwell [44] showing that Na+, K+-ATPase reduces its activity up to 50 due to oxidative stress. The present findings show that the rats exhibited a decrease in the activity of AChE in the unleaded group in comparison with either the control or the leaded groups. In addition to its function in degrading acetylcholine and modulation of neural function; AChE as a str
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Is the study of Gutteridge and Halliwell [44] showing that Na+, K+-ATPase reduces its activity up to 50 due to oxidative stress. The present findings show that the rats exhibited a decrease in the activity of AChE in the unleaded group in comparison with either the control or the leaded groups. In addition to its function in degrading acetylcholine and modulation of neural function; AChE as a str
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Anied with a higher tendency towards aggressive behaviour as a consequence to gasoline inhalation.11. 12.13. 14.AbbreviationsNa+, K+-ATPase: total adenosine triphosphatase; SOD: superoxide dismutase; AChE: acetylcholinesterase; GSH: reduced glutathione; TBARS: lipid peroxidation; DA: dopamine; NE: norepinephrine; 5-HT: serotonin; CNS: central nervous system; ROS: reactive oxygen species; MMT: meth
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Ither the leaded or unleaded group as compared with the control. On the contrary, dopamine was elevated in the cerebellum of leaded exposed group above both the unleaded gasoline and control. The fluctuations in the levels of dopamine in different brain areas may be related to the effects MMT which is an organic manganese (Mn) compound added to unleaded gasoline and the mechanisms of Mn neurotoxic