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Iposomesprotamine-DNA complexes), polymerized targetedliposomes, PEGylated liposomes, archaeosomes, ISCOMs (immune stimulating complexIposomesprotamine-DNA complexes), polymerized targetedliposomes, PEGylated liposomes, archaeosomes, ISCOMs (immune stimulating complex), virosomes, niosomes and many other, which are classified according to their [43] structures, composition, and preparation .
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N: a) by neutralizing the effects of LPS and thereby the response to it; and b) by limiting the extent of the inflammatory response to infection, thus compromising defenses against the infecting pathogen. The basis for these differences and their significance remain to be determined. We have shown in previously published work [12] that the clinical course of WT and SP-A-/- mice differs significant
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Ficient RNA replication resulting in almost 200000 RNA copies [27] from each RNAFicient RNA replication resulting in almost 200000 RNA copies [27] from each RNA template . Although replication-deficient particles provide a high level of safety, there is still a marginal risk of the generation of replication-proficient particles through nonhomologous recombination. To minimize this risk, spli
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As adjuvanted vaccine candidates and drug delivery systems, due to theirAs adjuvanted vaccine candidates and drug delivery systems, due to their ability to induce specific immune responses toward the encapsulated or surface-attached antigen, and to treat various diseases, including cancers, infectious, [46] and auto-immunity (reviewed in ). Currently, several liposomal formulations are comme
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Cular, intradermal, intranasal, vaginal routes); they ensure a rapid uptake ofCular, intradermal, intranasal, vaginal routes); they ensure a rapid uptake of the delivered molecule by immune cells (APCs and B cells), for MHC class I and class II presentation. Heterologous antigens exposed on the surface primarily evoke humoral immune responses, while the encapsulation approach give rise to CT
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Ro-fibrils. This was suggested to be crucial for HA mineral nucleation [59]. Self-assembly is thus another way that the IDP proteins can regulate the process of biomineralization.Author Manuscript Author Manuscript Author Manuscript Author Manuscript3. Potential Mechanisms of IDP Action: BiomineralizationThere must be precise reasons why so many IDP proteins are associated with mineralization. It
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NPs can be made from many different polymer types including naturalNPs can be made from many different polymer types including natural or synthetic polymers such as poly-d,l-lactide-co-glycolide (PLGA), polylactic acid (PLA), poly--caprolactone (PCL), chitosan, gelatin, poly-alkyl-cyano-acrylates (PAC), gamma polyglutamic acid (-PGA), hyaluronan [or hyaluronic [34,35,39] acid (HA)] . However